设为战游电子游戏大厅 | |
 
战游电子游戏大厅   企业新闻   人身防护   采样设备   运输设备   保存设备   检测设备   实验耗材   联系我们   在线留言
相关信息
  - 诚招各区域经销商
  - 关于举办病原微生物实验室安全管
  - WSCGZB2011-025文
  - 可感染人类的高致病性病原微生物
  - 长沙市动物防疫监督站防控应急物
  - Shipping and Re
  - 吉林省地方病第一防治研究所实验
  - 关于举办安徽省第五期实验动物从
  - 卫生部科教司举办实验室生物安全
  - 2011年全省医疗卫生机构性病
 
人气榜
  - 行业提示:危险品包装使用企业别
  - 新型布尼亚病毒:本市实行蜱虫咬
  - 卫生部办公厅关于加强高致病性病
  - 农业部紧急通知要求切实加强洪涝
  - 关于防止南非高致病性禽流感传入
  - 动物病原微生物菌(毒)种保藏管
  - 河北省卫生厅关于举办实验室生物
  - 佛山市举办2011年第一期实验
  - SPERIAN/斯博瑞安高性能
  - 杜邦纤维制耐切割点塑防滑手套
 
推荐
  - 深井采样器(智能)
 
 
Shipping and Receiving Biological Materials

日期:2011-7-29 11:32:33

1. Introduction
Biological materials, as described in paragraph 2 on page 1, must be properly identified and
packaged for shipping. Before a package is sent out you must consider the hazards that would
occur if the package were to be damaged during transport, including the possible release and
aerosolization of the specimen if the package were crushed. It is your responsibility to ensure
correct identification, classification, packaging, labeling, marking and documentation of all
shipments of potentially hazardous biological materials.
It is against the law to carry infectious/hazardous materials on an airplane. For example, if you
visit another lab and want to take an infectious substance back to your lab, you CANNOT carry
that sample on an airplane. It must be shipped by some other means like FedEx or UPS. You
cannot transport infectious/hazardous materials by ground, meaning by car or by subway. You
must properly package the material via DOT regulations explained in this packet.
Advance arrangements must be made with the recipient and carrier when shipping
infectious/hazardous materials, and permits obtained when importing infectious substances from
foreign countries. Failure to comply with federal and international regulations can result in
refusal of the shipment by the airline, penalties of fines, and/or jail.
This training manual will guide you through the steps of how to ship biological materials. The
regulations are updated frequently so it is necessary to repeat the training every two years to keep
up to date on changes.
2. Training Requirements
Federal rules require that anyone wishing to ship biological materials or dry ice must first have
shipping training. If you intend to pack biological materials or dry ice for shipment or fill out a
Shipper’s Declaration for Dangerous Goods (page 13) you must follow the training certification
requirements outlined below.
1. Read this training packet. This self-study training packet will provide general
guidelines relating to the regulations and training requirements applicable to shipping
biological materials and dry ice.
2. Have a current Bloodborne Pathogen Training (if applicable). Check Environmental
Services website http://www.nyu.edu/environmental.services/training.shtml#BBP. This
training is not required for everyone that ships biological materials or dry ice. It’s
important to check the website to determine if this is a requirement for you.
3. Who Regulates the Transport of Biological Materials?
Several agencies regulate the shipping of biological and hazardous materials. The regulations
are designed to protect those outside the institution who may come into contact with the package
or be exposed to the specimen in the event of an accident. This includes the shipper, carriers, the
public and the environment.
Some of the key agencies and regulations are listed below. A more detailed listing is included in
Appendix 1.
? The International Air Transport Association (IATA) Dangerous Goods Regulations apply to
shipments of infectious and hazardous substances via international and domestic air
transportation. Currently, IATA has the most stringent requirements for transportation of
infectious substances. http://www.iata.org/whatwedo/dangerous_goods. There have been
changes to 2005 IATA Regulations. For an explanation go here:
http://www.ehs.washington.edu/ftproot/iata05.pdf
? US Department of Transportation (DOT) Hazardous Material Regulations regulate the
domestic transport of infectious and hazardous substances. http://hazmat.dot.gov/ and
http://hazmat.dot.gov/training/rmgmt/InfectSubstances.pdf
? United States Public Health Service (PHS) Interstate Transport of Etiologic Agents regulates
domestic transport of infectious agents and Foreign Quarantine: Etiologic Agents, Hosts and
Vectors regulates the importation of infectious substances from foreign countries.
http://www.hhs.gov/
? United States Postal Service (USPS) Domestic Mail Manual; Etiologic Preparations covers
all shipments made through the US Postal Service.
http://www.usps.com/aviationsecurity/welcome.htm
? Occupational Safety and Health Administration Bloodborne Pathogens provides minimal
packaging and labeling requirements for the transport of blood and body fluids.
http://www.osha.gov/SLTC/bloodbornepathogens/index.html
Other helpful websites:
? Federal Express
http://fedex.com/us/services/options/express/dangerousgoods/declarationforms.html
? UPS http://ups.com/content/us/en/resources/select/sending/options/hazardous.html
4. How Do I Know If My Shipment Is Regulated?
If you intend to transport biological materials you should begin by determining which of the
following categories best describes your shipment. Shipments of each of the categories listed
below are regulated with the exception of Nonrestricted Specimens.
? Infectious Substance - This category is used for substances known to contain, or reasonably
expected to contain, pathogens that are known or reasonably expected to cause disease in
humans or animals. This includes:
a) Microorganisms (including bacteria, viruses, rickettsia, parasites, fungi)
b) Genetically modified (recombinant) microorganisms, hybrid or mutant
c) Specimens transported for initial or confirmatory testing for the presence of pathogens
d) Samples from a patient with an unknown disease
5
? Diagnostic Specimens have a relatively low probability of containing pathogens. When
specimens are transported/shipped for the purpose of routine screening tests, investigational
purposes, or diagnostic purposes for other than the presence of pathogens, they should be
packaged and shipped as diagnostic specimens. This includes human and animal material not
classified as infectious substances.
? Nonrestricted Specimens are specimens known not to contain pathogens. Only specimens
that have been proven by testing not to contain pathogens can fall within this category.
These specimens are not regulated and do not need to follow the packaging and labeling
requirements described below.
? Toxic Chemical - This category includes toxins from plant, animal or bacterial sources,
which do not contain any infectious substances and toxins that are contained in substances
that are not infectious substances. Shipping and receiving of substances in this category are
not covered in this training. If you will be shipping or receiving these substances contact
Environmental Services for guidance.
? Hazardous Material - This is a broad category including dry ice and genetically modified
microorganisms that do not meet the definition of infectious substances but are capable of
"altering animals, plants, or microbiological substances in a way that is not normally the
result of natural reproduction." With the exception of the materials noted here, the shipment
of hazardous materials is not covered in this training. If you think you will be shipping
hazardous materials, please contact Environmental Services for instruction.
Note: Genetically modified organisms and animals that contain them that are known or
suspected of being dangerous to humans, animals or the environment must not be
transported by air unless they are exempted by the States concerned under the provisions of
2.6.1 of the IATA Dangerous Goods Regulations. Please contact Environmental Services if
you need to ship these specimens.
5. What Quantities Can Be Shipped?
There are no exemptions for small amounts of infectious
substances. When you ship an infectious substance or
diagnostic specimen by passenger airline or the United States
Postal Service, the total amount in any triple package
(described below) that can be transported cannot exceed 50 ml
or 50 grams.
When shipped by cargo airline, the total quantity per triple
package cannot exceed 4 liters or 4 kg, and the package must
have the label seen here displayed on the outer packaging.
Exception: There are special quantity limits for the following items only, as long as they are
not contaminated with a disease that is readily transmitted and for which there is no current
treatment. 1) Body fluids can be shipped at 1 liter per primary container and 4 liters net per
package on both passenger and cargo aircraft; 2) There are no quantity limits for body parts,
organs, or whole bodies.
6
6. How Do I Package Materials?
Potentially hazardous biological materials must be packed according to the regulations. They
must be packaged to withstand leakage of contents, shocks, temperature and pressure changes
and other conditions that can occur during ordinary handling in transportation. Certified
containers purchased from commercial suppliers must be used, regardless of the mode of
transportation. Appendix 2 lists a number of vendors that supply containers used in infectious
material transport. When ordering shipping supplies specify what category of materials you will
be shipping: infectious substances, diagnostic specimens, dry ice, regular ice, etc. Different
categories have slightly different packaging needs but all follow the basic triple packaging
requirements described below.
When you receive your packing materials, follow the instructions and save any testing
documentation the company sends. If you are going to reuse packing materials, make sure you
use the materials for the purpose they were originally designed.
Figure 1 depicts the principle of triple packaging (primary receptacle, watertight secondary
packaging, durable outer packaging) upon which all regulations are built. Infectious substances,
diagnostic specimens, and genetically modified microorganisms that fall under the category of
hazardous materials must be packaged in this way.
Primary Receptacle. The primary receptacle contains the biological material and must be
watertight to prevent leakage. The primary receptacle must be labeled with the name of the
specimen. Primary receptacles may be made of glass, metal, or plastic and include screw-cap
tubes, flame-sealed glass ampules, or rubber-stopped glass vials fitted with metal seals. Petri
Figure 1. Packing and Labeling of Biological Materials

plates cannot be used as primary receptacles. Lyophilized substances can only be shipped in
flame sealed glass ampules or rubber stopped glass vials with metal seals. Positive means of
7
ensuring a leakproof seal, such as a heat seal, skirted stopper, or metal crimp seal must be
provided. Screw caps may be fastened with tape, shrink seals, or other comparable material.
Although glass is allowed, it is preferable to use plastic primary receptacles.
Secondary Packaging. One or more primary receptacles are placed in watertight secondary
packaging. The primary receptacle or the secondary packaging must withstand, without leakage,
an internal pressure differential and temperature range as described in the United Nations (UN)
packaging specifications and performance tests. The secondary packaging should also bear a
label with the name, address, and telephone number of the shipper, as well as the name of the
specimen.
Absorbent Material. Absorbent material must be placed between the primary receptacle and
secondary packaging. Multiple primary receptacles must be individually wrapped to prevent
contact between them. The absorbent material must be sufficient to absorb the entire contents of
the primary container(s).
Itemized List. An itemized list of contents must be enclosed between the secondary packaging
and the outer packaging.
Outer Packaging. Outer packages must be at least 100 mm (4 in) in the smallest overall external
dimension in order to bear the required markings and labels. Outer packaging must be of
adequate strength for its capacity, mass, and intended use, and must be capable of meeting the
rigorous performance tests and be marked with a UN specification mark.
Overpacks. An overpack can be used to combine several triple packages
into one large package. Each triple package inside the overpack must be
properly labeled and marked. The outside of the overpack must have the
same markings and labels as the triple packages packed within, with the
exception of the UN specification mark. This must not appear on the
overpack. The overpack must also be marked with the statement “Inner
Packages Comply with Prescribed Specifications” and the total net
quantity in the overpack must be listed next to the proper shipping name.
An overpack must not contain any other goods with infectious materials except refrigerant.
Ice and Dry Ice. If your material needs to be shipped in ice or dry ice, special packaging must
be purchased. If ice is used, the packaging must be leakproof. If dry ice is used, the outer
packaging must permit the release of carbon dioxide gas. The ice or dry ice must be placed
outside the secondary packaging and interior supports must be provided to secure that the
secondary packaging stays in the original position after the ice or dry ice has dissipated.
Liquid Nitrogen. Biological materials can be shipped in liquid nitrogen or dry shippers, which
are insulated packages containing refrigerated liquid nitrogen fully absorbed in a porous
material. Special packing regulations apply to shipments containing nitrogen. Contact
Environmental Services if you need to ship specimens in nitrogen.
9. How Do I Mark and Label My Package?
Marking and labeling requirements are based on the type of material you are shipping. For all
classes of substances, the proper specimen name is required on primary, secondary, and outer
packaging and the shipper's and recipient's addresses are required on secondary and outer
packaging. Labels on the outer packaging must be placed on the same side of the package as the
proper shipping name. The outer packaging must be of sufficient size to accommodate all labels
placed on a single surface and labels must not overlap. Below marking and labeling
requirements for the outer packaging are specified by the type of material being shipped.
9.1 Infectious Substances
Each outer package of infectious substances must be marked with the following:
a) The proper shipping name and UN Number for all hazardous contents. (see Table 2)
This includes the proper shipping description, the technical name of the infectious
substance and the UN number. For example: "Infectious Substance Affecting
Humans (Herpesvirus simiae) UN 2814".
b) The full name, address, and phone number of the shipper and the recipient.
c) The name and telephone number of the person designated as the "Responsible
Person" for the package.
d) UN specification mark. This mark includes the United Nations packaging symbol,
the type of packaging, the hazard class (6.2 for infectious material), the year of
manufacture of the packaging, the authorizing agency and the manufacturer. This
marking is preprinted on commercially available packaging for infectious substances.
(See Appendix 2 for vendors) This number should not appear on an overpack.
Each package of infectious substances must have the following labels and documents on the
outside of the shipping container, placed on the package in the same orientation as shown here.
a) Class 6, Division 6.2 “Infectious Substance” label.
This diamond-shaped label should contain the
telephone number of the CDC in Atlanta to which
damaged or leaking packages should be reported.

 

 
 

战游电子游戏大厅(C)版权所有京ICP备09076172号
友情链接:· 酷帝网站目录 · 网站排行榜
漂浮广告